There is a reason that the vast majority of fantasy football leagues don't include Week 17: things get weird. It's right up there with the first couple weeks of the season as the hardest to predict because you don't know for sure who is actually going to play or for how long, and that is especially true this year with a spike in COVID-19 cases after Christmas. Some of the actual spreads in Las Vegas have changed by quite a bit due to some news, but the lines in the CBS Pick 'Em Pool are still the same. Keeping those factors in mind, here goes nothing:
Home Favorites
Bills -3.5 versus Dolphins
1/3 UPDATE: Early morning reports indicate that Buffalo won't play their starters for much of the game, so I'm switching this pick to Dolphins +3.5.
Browns -7.5 versus Steelers
Patriots -3.5 versus Jets
Colts -14.5 versus Jaguars
Road Underdogs
Falcons +6.5 at Buccaneers
Cardinals +1.5 at Rams
Home Underdogs
Bengals +11.5 versus Ravens
Texans +7.5 versus Titans
Broncos +2.5 versus Raiders
Road Favorites
Vikings -6.5 at Lions
Cowboys -2.5 at Giants
Saints -6.5 at Panthers
Packers -5.5 at Bears
Chargers -3.5 at Chiefs
Seahawks -4.5 at 49ers
Washington -1.5 at Eagles
Last week: 7-9
Season total: 124-116
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